More Spaces for Early Intensive Behavioural Analysis Program

first_imgChildren with autism preparing to start school in 2016 at age six will benefit from the Early Intensive Behavioural Intervention program. In September government will add between 20 and 25 new spaces in the program, creating a total of 110 spaces. This means 110 children will be able to receive the program each year. Government will now be investing a total of $10 million each year in this program. “Before, our daughter would enter a crowded room, go to a corner and put her fingers in her ears. Now she walks in and wants to be the centre of attention,” said Lori Fancy, whose six-year-old daughter finished the program in May 2014, and started school the following September. “If I had to do it all again, I would do it in a heartbeat. On the first day of school, she was the first one in line and overall she’s transitioned into school seamlessly.” There are currently 25 children on the waitlist who will enter school at age six in 2016. “As parents, we all want what’s best for our children. For children with autism, this program provides the best start possible before they begin school,” said Health and Wellness Minister Leo Glavine. “I recognize it can be a difficult choice for some families to delay school entry, but this program provides valuable skills that will better prepare these children for the learning environment at school.” Last fall, Mr. Glavine appointed an expert panel to review the program to ensure the province was providing the best treatment possible to children with autism before they start school. The panel concluded that the program is effective in helping children develop communications skills, follow directions, pay attention and control their emotions. These skills are often very weak or non-existent for children with autism, and they are important for success at school. The report is available at novascotia.ca/dhw . “Giving children the best start in the early years will help them reach their full potential,” said Mr. Glavine. The Early Intensive Behavioural Intervention program began in 2005, to help children with autism get treatment before they entered school. At the time, about one in 150 people were diagnosed with autism, according to the Center for Disease Control in Atlanta. That number has now more than doubled, with an estimated one in 68 people being diagnosed.last_img read more

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UK economys worst month since Brexit vote

first_imgLondon: A closely watched survey of business activity in the UK is showing that the economy contracted in June at its steepest rate since the immediate aftermath of the country’s vote three years ago to leave the European Union. The survey from financial information firm IHS Markit and The Chartered Institute of Procurement & Supply also found the second-steepest fall in output since the height of the global financial crisis a decade ago. The survey’s main “all-sector” purchasing managers’ index fell in June to 49.2 from 50.7 the previous month.last_img read more

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Ayodhya dispute Rajeev Dhavan objects to daily hearings

first_imgNew Delhi: On the fourth day of the Ayodhya dispute hearing on Friday, senior advocate Rajeev Dhavan raised an objection to the daily hearing in the case. Dhavan, who is representing a Muslim party, said it will be difficult to prepare arguments in the case if the top court conducts hearings on all five working days in a week. “We don’t get time for preparation of arguments,” he said, adding that this was the beginning of the first appeal. He termed the curent set-up of hearings as “inhuman” and “practically impossible” and said: “Cannot go on like this.” Chief Justice Ranjan Gogoi assured Dhavan that the apex court will look into his grievances and revert to him at the earliest.last_img read more

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A Glimpse Inside Celebrity Charities and Fundraising Events

first_imgIt’s refreshing to see celebrities get glammed up for more than just a red carpet walk or to accept an award. Many stars also go big for the greater good of society. No doubt, celebs like to give back. And the abundance of star-studded charity events happening seemingly every day is proof of that. From environmental causes to child and animal welfare, celebrities feel strongly about their favorite charities.For example, Leonardo DiCaprio’s passion for the environment and educating people on global warming is so strong that it was part of his Oscars speech. Matt Damon is the co-founder of Water.org, a nonprofit organization that has positively transformed more than four million lives around the world through access to safe water and sanitation. Country singer Miranda Lambert took action for her passion for animals by starting her own charity called MuttNation Foundation. This charity aims to end animal cruelty, neglect and homelessness.With an endless list of celebrity-backed charity events, savoring the high life seems to be celebrities’ favorite way to give back. Caviar and champagne in exchange for saving the world? Sounds like a win-win.Get the inside scoopAccording to the Hollywood Reporter, celebrity charity events come with a specific set of rules. From planning the guest of honor to dealing with party crashers to getting the media there, event planners know which hoops to jump through to make an event a success. And they know how to get the celebrities there – with the promise of good press and freebies. Yes, even the rich and famous enjoy free swag now and then.But bartenders get, perhaps, the best glimpse of it all by brushing shoulders with celebrities. From learning their go-to drinks to seeing how they tip to getting chummy with them, waiting on celebrities comes with stories that can last a lifetime.One lucky bartender downed a shot with Indiana Jones and said: “I did a shot with Harrison Ford. Put that on my tombstone.”Drink like a celebrityIf all this glamorous charity event talk makes you want to give back, there are an abundance of charities and worthy causes to devote your time, money and effort to. And if it makes you yearn for the finer things in life, well, you can do that, too. Right in your own home.You don’t need to be surrounded by the paparazzi to drink like a celeb. Create your very own celebrity-worthy cocktail in your kitchen. Most would agree that the martini is one of the most glamourous and celebrity-loved drinks around (hello, James Bond!). Whether you take it shaken or stirred, dirty or dry, you can drink like a star with this quick video tutorial on how to make the perfect martini.Not the martini type? How about a Cosmo, a la the Sex and the City gals? Drink like Carrie Bradshaw with this delicious recipe.It’s no secret that Jennifer Aniston loves a good margarita. Whip up a batch of her favorite libation (with her exact recipe) to enjoy with your friends.While we may not all be celebrities, you can drink like one. And, more importantly, you can give back to worthy charities of your choice just like the celebs do. Because celebrity or not, everyone is worthy of giving back.Black tie optional.last_img read more

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Scotland Yard officer fired over letting Greek homeless man out to die

first_img Facebook Twitter: @NeosKosmos Instagram A Scotland Yard police constable (PC) has been dismissed from her job without notice after she evicted a man who sought shelter at her police station on a cold night.PC Bhupinder Kalsi a UK citizen of Indian background was laid off for “failing to exercise reasonable care in her treatment and monitoring of a homeless man after ejecting him from a police station in west London” according to a Metropolitan Police Unsatisfactory Police Performance meeting on Monday.The man who was evicted from the station was reportedly Greek national Pericles Malagardis, who was sleeping at Heathrow Airport and had gone to Uxbridge police station to collect his dog on a cold day.The 63-year-old died of hypothermia after he was made to leave the police station for smoking back in 2016.After two years of investigating the case, the Independent Office for Police Conduct (IOPC), referred the case to the Crown Prosecution Service (CPS) to consider charges of gross negligence manslaughter.“We found there was not enough evidence to prosecute for any offences and took no further action,” the CPS said dismissing the woman on unsatisfactory performance.Meanwhile, an internal disciplinary panel found that Kalsi “did not provide information requested by the London Ambulance Service regarding actions taken to support Mr Malagardis, and failed to follow instruction and training when dealing with unresponsive casualties.”She did not appear to have asked the man to just stop smoking indoors or checked up on him after evicting him into adverse weather conditions and did not go to him after he was found unconscious on the pavement.As stated in the inquest panel report “PC Kalsi was viewing a DVD whilst on duty, following Malagardis’ ejection from the front office area of the police station. Another police station staff member is facing a separate disciplinary hearing over negligence regarding the same incident.Once the internal Metropolitan Police reviews are completed, an inquest into the conditions of Malagardis’ death is to take place.last_img read more

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Le bilan carbone du projet Grand Paris pointé du doigt

first_imgLe bilan carbone du projet Grand Paris pointé du doigtAlors que le projet Grand Paris prévoit la création de nouvelles lignes de métro, un rapport du Cabinet conseil Carbone 4, commandité par la SNCF, pointe du doigt le bilan carbone qu’engendrerait un tel chantier.Réhabiliter des lignes de transports en commun déjà existantes en Ile-de-France serait bien moins polluant, et coûteux, que lancer la construction de nouveaux tracés, estime le cabinet. “Les projets trains-trams, de rénovation du RER et des solutions alternatives sont des choix de bons pères de famille, alors que la construction d’un métro autonome du Grand Paris tant dans un contexte de récession que de croissance économique apparaît comme risqué”, a souligné Hélène Le Téno, consultante de Carbone 4, citée par l’AFP.Lors de la présentation du rapport, elle a précisé que la construction d’un seul tunnel pour accueillir une nouvelle ligne engendrerait quelque 40.000 tonnes de CO2 par kilomètre. A ces émission, il faut ajouter celles produites par le tunnelier, la production du béton et des aciers, mais aussi le déblayage du chantier.Pour Jean-Marc Jancovici, fondateur de l’association The Shift Project, qui oeuvre en faveur d’une transition vers un monde sans carbone, les milliards d’euros nécessaires au financement du Grand Paris devraient être dépensés d’une toute autre façon. Cet argent serait selon lui plus utile s’il permettait de “financer  une super prime à la casse par laquelle on dit à chaque ménage francilien : ‘On vous paye une voiture neuve si elle consomme pas plus d’un litre et demi au cent kilomètres à la place de la vieille'”. Et de souligner qu’en plus d’éviter d’importantes quantités de CO2, un tel dispositif  réglerait “le problème de tout le monde et pas seulement des 3% de gens qui vont devoir basculer de la voiture sur le train”.Pour l’heure, deux projets ont été proposés pour le Grand Paris. Le premier, élaboré par l’Etat, prévoir la construction d’une double boucle de métro automatique parcourant 155 kilomètres autour de Paris. Le second a été soumis par l’Ile-de-France et le syndicat des transports de la région, le Stif. Il  est cette fois question d’une rocade de métro en proche banlieue, Arc Express.Le 25 janvier 2011 à 18:44 • Emmanuel Perrinlast_img read more

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Le Japon forcé de limiter sa consommation électrique

first_imgLe Japon, forcé de limiter sa consommation électriqueAprès l’accident de Fukushima Daiichi suite au séisme et au tsunami du 11 mars dernier, les Japonais se voient contraints de réduire leur consommation d’électricité pour compenser l’arrêt des réacteurs nucléaires. Depuis le tsunami et la catastrophe survenue à la centrale nucléaire de Fukushima en mars, les Japonais sont obligés de s’imposer un certain nombre de restrictions pour limiter leur consommation électrique. Les escalators sont arrêtés, les lumières restent éteintes, les climatiseurs ne fonctionnent plus et les employés sont placés en vacances forcées, rapporte TV5monde.Les habitants de Tokyo et de la région du nord-est se voient obligés de réduire de 15% les dépenses d’électricité à partir d’aujourd’hui. Les services publics et les entreprises se sont d’ailleurs préparés à une très faible distribution énergétique jusqu’en septembre. Ainsi, moins de trains circuleront alors que, dans les gares, les distributeurs de boissons cessent par intermittence de refroidir leurs stocks.Habituellement, à cette période de l’année où il fait très chaud au Japon, les systèmes de climatisation tournent à plein régime. Il s’agit désormais d’un luxe que la troisième puissance économique mondiale ne peut plus se permettre depuis le désastre du 11 mars. En effet, la température de l’air conditionné a maintenant été partout relevée de 2°C, à 28°C. Appelées à réduire l’utilisation de la climatisation, les familles se sont ruées sur les ventilateurs. Les importations, à Tokyo, ont bondi de 70% en mai sur un an.Dans les immeubles de bureau, les couloirs restent éteints et les employés qui viennent encore travailler se déplacent à une heure matinale où les températures restent fraîches. Des administrations poussent leurs salariés à prendre des congés d’été ou proscrivent temporairement les heures supplémentaires, du jamais vu au Japon où le travail est roi. Les usines d’automobiles restent fermées les jeudis et vendredis et reprennent la production le week-end, lorsque la tension sur le réseau est inférieure.L’été devrait être caniculaire, un enfer en perspective pour les JaponaisGrâce à ces diverses mesures d’économies d’énergie dans tous les secteurs, les compagnies d’électricité espèrent éviter des coupures de courant localisées ou, pire, un arrêt généralisé de l’alimentation. “Ces mesures d’économie et de réorganisation des plages de travail devraient être efficaces, mais nous ne pouvons écarter à 100% le black-out”, estime Ben Wedmore, chercheur à MF Global. Mauvaise nouvelle, l’été devrait être caniculaire et le mercure a déjà atteint les 35°C à Tokyo mercredi, les capacités des quatre réacteurs restants de Tepco (qui continue à desservir la capitale) étaient au bord de la saturation.Pour faire face, l’entreprise a commandé en urgence des turbines à gaz et compte acheter du courant aux usines voisines équipées de groupes électrogènes. La situation devrait encore se compliquer à partir d’août, lorsque deux réacteurs supplémentaires devront être stoppés pour être révisés et entretenus. “La situation pourrait être tendue cet hiver”, a reconnu le PDG, Toshio Nishizawa.À lire aussiLa fusion nucléaire pourrait bien devenir prochainement une réalitéA côté de cela, les autorités de l’ouest et du sud du pays hésitent à donner le feu vert pour redémarrer les réacteurs des usines, pour le moment en standby. Pour l’heure, seuls 19 réacteurs sur 54 fonctionnent alors que l’énergie nucléaire fournissait 30% de l’énergie totale à l’archipel avant le 11 mars. Le chercheur de MF Global pense qu’”à court terme, les compagnies produiront davantage d’électricité avec du gaz, du charbon et du pétrole”, ce qui va à l’encontre de l’objectif de réduction de 25% des émissions de gaz à effet de serre, d’ici 2020 par rapport à 1990, comme l’avait annoncé le Japon dans le cadre de la lutte contre le réchauffement climatique.Alors que l’avenir du nucléaire est sur la sellette, le Premier ministre de centre-gauche, Naoto Kan, prépare une loi sur les énergies renouvelables. Il souhaite élever leur part de 10% aujourd’hui à 20% d’ici à 2030 au plus tard, indique l’AFP.Le 1 juillet 2011 à 13:58 • Emmanuel Perrinlast_img read more

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Quand Samsung Microsoft ou Google sinvitent au SXSW

first_imgQuand Samsung, Microsoft ou Google s’invitent au SXSWLorsque la Silicon Valley se déplace au Texas, le résultat donne le SXSW. Découpé en trois secteurs, le festival réserve une large partie à segment nouvelles technologies via le SXSW Interactive. De plus en plus, les grandes entreprises technologiques investissent le SXSW. Par exemple, en 2007, Twitter, encore peu connu, avait fait sensation. Deux ans plus tard, c’est au tour de Foursquare de venir faire un tour au SXSW. “C’est plutôt un signe avant-coureur dans un contexte où nous sommes submergés par des technologies basées sur la localisation. Et nous devrions encore en voir de nombreuses pour cette édition 2012”, rappelle Hugh Forrest, directeur du SXSW Interactive.À chaque constructeur son villageCertains constructeurs ont même décidé de monter leurs propres villages au sein du festival, histoire qu’on ne puisse pas leur passer à côté explique le Tucson Citizen. Ainsi, Microsoft et Samsung ont déjà leurs stands pour toucher le plus de clients potentiels possible. Samsung a d’ailleurs fait une démonstration du jeu Angry Birds Space sur son Galaxy Note, lors d’une conférence.De son côté, le village Google est une petite enclave, située sur les bords extérieurs de la ville d’Austin. Généralement déserté pendant la durée des SXSW Music et SXSW Film, il se remplit dès l’ouverture du SXSW Interactive.Et Google ne fait pas les choses à moitié. Construit sur le modèle du fameux Googleplex en Californie, le village est constitué de quatre parties:  l’Android House, la Maps House, la Developers House et de la Discovery House.La firme de Mountain View a décidé d’accroître sa visibilité au SXSW pour faire face à ses concurrents, Facebook et Microsoft, qui ont augmenté leur activité au festival.Le Village Start-UpÀ lire aussiMaladie de Charcot : symptômes, causes, traitement, où en est on ?L’édition 2012 verra également la création du village Start-Up. Selon Hugh Forrest, “cela devrait donner aux start-up l’impulsion nécessaire à leur implantation sur le marché” rapporte le Tucson Citizen. Entreprises technologiques, chaînes alimentaires, chaînes télévisées… toutes cherchent à être représentées au village Start-up. En effet, Jen Brown, directeur digital chez Today, explique le phénomène: “c’est l’endroit où tout le monde discute des dernières innovations, et il y a de nombreuses idées directrices qui émergent dans le village”.Reid Hoffman, co-fondateur de LinkedIn et un des esprits les plus intelligents de la Silicon Valley ne se rend, lui, qu’aux conférences qui lui sont utiles et cela inclut celle de TED, AllThingsD, TechCrunch, Disrupt ou LeWeb. Pour lui, “le SXSW est super opportunité pour LinkedIn, mais aussi pour moi, en tant qu’investisseur et théoricien”, cite le Tucson Citizen.Le Telegraph a révèlé que Jimmy Wales, co-fondateur de Wikipedia, représentera le gouvernement britannique pour tout ce qui concerne la transparence en ligne. De leur côté, Google et Facebook ont décliné l’invitation à la conférence sur la vie privée en ligne. Le réseau social a annoncé “n’avoir aucun membre de son équipe présente au SXSW qui puisse discuter du problème”. La firme de Mountain View a, quant à elle, avancé un litige en cours avec le groupe Electronic Privacy Information Center, également programmé sur la conférence. Le 13 mars 2012 à 10:30 • Maxime Lambertlast_img read more

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Grama Vastavya 20 Ktaka CM holds meeting with officials ahead

first_imgRaichur: Karnataka Chief Minister HD Kumaraswamy on Wednesday held a meeting with officials before his ‘village stay programme’ in Raichur. The Karnataka Chief Minister commenced his ‘Grama Vastavya 2.0’ or ‘village stay programme’ from Northern Karnataka on June 21. The agenda is an extension of the “Grama Vastavya” programme, first started in Kumaraswamy’s regime as the state’s chief minister from 2006-2007 with BJP’s B.S. Yeddyurappa as his Deputy Chief Minister. Also Read – After liquor, Bihar bans ‘pan masala’ as well Advertise With Us After his party, Janata Dal (Secular), faced a severe drubbing in the recently concluded Lok Sabha elections, the programme focuses on strengthening the party’s relations with the locals and noting the plight of the common man. Kumaraswamy said the village stay scheme will pave the party’s way to an enhanced political standing. The Chief Minister also met his party leaders, along with Siddaramaiah to lay out an action plan for the smooth functioning of the presently ruling Congress-JD(S) government in the state. The landslide victory of BJP in the 2019 Lok Sabha elections with 25 of the 28 seats is believed to be a cause for the re-establishment of the programme. JDS won only one seat in the elections. In Raichur, Kumaraswamy will inaugurate as many as 36 developmental projects.last_img read more

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IFC issues 30 million in 15year Masala bonds

first_imgPricing DateMarch 14, 2016 IFC Masala bond summary terms and conditions SizeINR 2 billion ($ 29.8m) The International Finance Corporation (IFC), one of the five key organisations of the World Bank Group, issued $30 million in 15-year Masala bonds in the international market March 14, said a statement from IFC.The 15-year Masala bond marks the longest dated offshore rupee bond to be ever issued by the corporation, while it has previously issued similar bonds in maturities of three, five, seven, and 10 years.Masala bonds are rupee-denominated instruments sold only to offshore investors to help raise resources to promote private sector development in India.The IFC is the world’s largest global development institution focused on mobilising funds from developed geographies and internationally to help the private sector in emerging markets such as India.The statement said that the 15-year Masala bonds will be listed on the London Stock Exchange and proceeds of the bonds will be used to advance private sector development in India.These bonds are expected to help deepen India’s capital markets by extending the yield curve. It will also help set a benchmark for future rupee-bond prices based on these varied ranges of maturities issued, said an earlier press release.”With our latest Masala bond issuance, IFC has created an offshore rupee-market yield curve that stretches from three to fifteen years, deepening the market and making it more resilient,” said IFC’s VP and Treasurer Jingdong Hua. “This sends a clear signal that investor demand for high-quality assets in India remains strong, despite global financial uncertainties.””Lasting prosperity depends on strong and efficient capital markets,” added Hua.The corporation has played a prominent role in India’s capital-markets development, rolling out a $3 billion rupee-denominated Masala bond programme over the past two years. The institution has invested proceeds of the Masala bond programme so far in 11 private sector development projects in India. These triple-A-rated 15-year Masala securities too are issued under the same $3 billion Masala bond programme.In move to help Indian citizens to have a stake in their country’s development, IFC has also issued Maharaja bonds: a $2.5 billion programme for issuances in India’s domestic capital market, said the statement.IFC Masala bond summary terms and conditionsIFC Masala bond summary terms and conditionsIFC Masala bond summary terms and conditionsPricing DateMarch 14, 2016IFC Masala bond summary terms and conditionsSettlement DateMarch 21, 2016IFC Masala bond summary terms and conditionsMaturity DateMarch 21, 2016IFC Masala bond summary terms and conditionsSizeINR 2 billion ($ 29.8m)IFC Masala bond summary terms and conditionsCoupon7.10% p.a.IFC Masala bond summary terms and conditionsListingLondonIFC Masala bond summary terms and conditionsArrangerJP Morgan Securities plc Settlement DateMarch 21, 2016 Maturity DateMarch 21, 2016 ListingLondon Coupon7.10% p.a. ArrangerJP Morgan Securities plclast_img read more

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Beyoncés Production Company Sued Over Website Accessibility

first_img LGBTQ+ Video Creators Sue YouTube, GooglePresidential Hopeful Tulsi Gabbard Sues Google Over Alleged Censorship So far, 2019 hasn’t been good to Beyoncé Knowles. Her company Parkwood Entertainment has been hit with a class-action lawsuit claiming the superstar’s website, Beyonce.com violates the Americans With Disabilities Act by denying visually impaired users equal access to its products and services, according to the Hollywood Reporter.The plaintiff, New York resident Mary Conner, claims the website isn’t fully accessible for her and for millions of others who have visual impairments.Website accessibility requires photos to be coded with alt-text so that screen-readers used by visually impaired users can speak the alternative text. Conner claims that because Beyonce.com is “an exclusively visual interface” she’s unable to browse the site and make online purchases without the assistance of a sighted companion, THR reported.AdChoices广告“There are many important pictures on beyonce.com that lack a text equivalent … As a result, Plaintiff and blind beyonce.com customers are unable to determine what is on the website, browse the website or investigate and/or make purchases,” Conner’s attorney Dan Shaked wrote in the complaint.Conner is described in the filing as having “no vision whatsoever.”Shaked describes music as “the one and only form of entertainment that truly presents an even playing field between the visually impaired and the sighted.”He added: “Plaintiff dreams of attending a Beyonce concert and listening to her music in a live setting. However, when she browsed the Beyonce.com website, she encountered numerous barriers which limited her accessibility to the goods and services offered on the website.”The complaint also lists issues that include the lack of accessible drop-down menus and navigation links, and the inability to navigate using a keyboard instead of a mouse.The lawsuit includes “all legally blind individuals in the United States who have attempted to access Beyonce.com and as a result have been denied access to the enjoyment of goods and services offered by Beyonce.com, during the relevant statutory period.”Conner is seeking a court injunction that would require Beyoncé’s company to make the site accessible to blind and visually impaired customers in accordance with ADA rules, and is asking for compensatory damages for those who have “been subject to unlawful discrimination.”Read the full complaint here.More on Geek.com:Netflix, WB Settle ‘Satanic’Lawsuit Over ‘Chilling Adventures of Sabrina’Utah Must Cover $475K in Legal Fees After Losing ‘Deadpool’ SuitWatch: Meet the Inspiring Blind Gamer Who Beats Pros at ‘Street Fighter V’ Stay on targetlast_img read more

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Cytochrome P450 synthetic analogs are temperaturedependent valence tautomers

first_img Explore further Citation: Cytochrome P450 synthetic analogs are temperature-dependent valence tautomers (2016, June 24) retrieved 18 August 2019 from https://phys.org/news/2016-06-cytochrome-p450-synthetic-analogs-temperature-dependent.html Revealing the ligand-hole localization behaviors in oxides with unusual high-valence Fe Ctochrome P450. Credit: Wikipedia Something that has puzzled chemists for many years is why synthetic analogs of cytochrome P450 are much more sensitive to degradation from O2 than its enzyme form. In an effort to better understand this discrepancy Pradip Kumar Das, Subhra Samanta, Ashley B. McQuarters, Nicolai Lehnert, and Abhishek Dey of the Indian Association for the Cultivation of Science and the University of Michigan examined the electronic structure of four different iron porphyrin complexes using resonance Raman, electron paramagnetic resonance, and 1H NMR spectroscopy. They found that the iron porphyrins are temperature dependent valence tautomers, ferric thiolate and ferrous thiyl, which may play a key role in O2 sensitivity. Their research appears in the Proceedings of the National Academy of Sciences.The stable form of the cytochrome P450 active site contains Fe3+ coordinated to a thiolate. It will only react with O2 when Fe3+ is reduced to Fe2+. However, in synthetic analogues the Fe3+ porphyrin complex degrades in the presence of O2. Oxygen will oxidize the thiolate ligand unless it is sterically protected. The difference between the enzyme and the synthetic analogs is likely due the electronic structure. To understand the electron structure of these iron porphyrins, Das, et al. tested four known compounds with variances in the thiolate ligand. The first compound contains an alkyl thiolate ligand and is unstable in air. The second compound has a bulky aliphatic complex that sterically protects the thiolate group and is stable in air. The third complex has a benzylic group attached to the thiolate and is stable in air. The fourth compound has an aromatic thiolate and is unstable in air.Each of these compounds was tested with resonance Raman (rR), electron paramagnetic resonance (EPR), and 1H NMR spectroscopy. Resonance Raman for all four compounds indicated that there are two different species present at room temperature, but only one present at low temperatures. The two species have frequencies suggestive of a high- and low-spin Fe3+ state and a high-spin Fe2+ state. Low temperatures seem to only contain compounds with Fe3+. These results were corroborated with EPR spectroscopy which indicated the presence of a radical species at room temperature. This radical species is likely the Fe2+—RS• radical, or the thiyl radical, a valence tautomer to the Fe3+—RS- complex. Proton NMR studies, while perhaps indicative of two species present at room temperature, were less conclusive. Variable temperature resonance Raman and variable temperature EPR studies showed that as the temperature decreases, less Fe2+ was present. However, Das, et al. found that the signal is reversible. As temperature increased, the radical signal returned. In all four compounds there seemed to be a valence tautomerism between Fe3+ thiolate and Fe2+ thiyl radical. Analysis of the temperature studies indicated that the Fe3+ thiolate tautomer is energetically favored while the Fe2+ thiyl radical is entropically favored.Solid state studies confirmed that there is apparently a change in geometry in the solution state that does not occur in the solid state, again, indicating a tautomer.Finally, the aliphatic and benzylic complexes were immobilized on a silver surface to test the effects of hydrogen bonding on the stability of the iron porphyrins. In an organic solvent, such as THF, the complex degrades in the presence of O2. However, when only 0.5% water, by volume, was added, then the complex is stable in the presence of O2. Hydrogen bonding must play a role in stabilizing the Fe3+ thiolate complex.This research provides essential insight to a decades-long mystery regarding synthetic analogs of cytochrome P450. Iron porphyrin analogs exist as a valence tautomer at room temperature, which likely enhances the compound’s sensitivity to O2. Furthermore, hydrogen bonding likely plays an essential role in stabilizing the enzyme’s ground state. More information: Pradip Kumar Das et al. Valence tautomerism in synthetic models of cytochrome P450, Proceedings of the National Academy of Sciences (2016). DOI: 10.1073/pnas.1600525113center_img This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Cytochrome P450 is a well-known family of enzymes that are involved in drug metabolism. The active site contains a heme chemical structure in which an iron atom is bound to the heme cofactor within the enzyme. The oxidation state of the iron plays a key role in catalysis, notably in oxidizing organic compounds using O2, and an iron-sulfur bond is a key component to the enzyme’s function. Journal information: Proceedings of the National Academy of Sciences © 2016 Phys.orglast_img read more

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Firearms Museum Focuses On Gun Safety History

first_img https://ondemand.npr.org/anon.npr-mp3/npr/wesun/2019/08/20190825_wesun_firearms_… Firearms Museum Focuses On Gun Safety, History And Culture by NPR News Kamila Kudelska 8.25.19 8:46am Tucked away in the northwest corner of Wyoming is one of the largest gun collections in the world: The Cody Firearms Museum. But it’s recently gotten a makeover, moving away away from being a monument to guns and toward being an educational space on gun safety, history and culture. The museum is located at the Buffalo Bill Center of the West alongside four other museums and near the east entrance to Yellowstone National Park. So often, people just happen upon it. That was the case for Kim Cato and her family, visiting from Idaho. “We were not planning to go in here,” Cato said. Cato said that’s because of her own previous experience with the museum. “I was here as a child and my dad dragged me through it and it was just rows and rows of guns and it was just not exciting.” But now, the recently renovated museum seemed more intriguing. So Cato and her husband Kevin, their 12-year-old son, Tyson, and 15-year-old daughter, Jillian, took a tour with Ashley Hlebinsky, the curator. People and technology”So we’re actually going to start right here,” said Hlebinsky, as she led the family to the mission statement plastered in big letters on a wall at the entrance of the museum. “A lot of times when you talk about firearms history, you think about the history of technology, but it’s also a history of people, and with that history of people it can be good, bad and indifferent.” In an effort to address the good, the bad, and the indifferent, the first gallery is focused on basic firearm safety, especially where kids are involved. There’s an interactive table and the first thing you see, “Do you know what to do if they [children] are out in the real world and they encounter a real firearm?”Under the question, a set of rules are mounted at a height designed to be read by children. They include: Stop. Don’t touch the firearm. Get an adult or a law enforcement officer. Cato found these guidelines really helpful. “We had an experience where a child climbed over a fence and handed my son a gun,” Cato said. “And didn’t you try to shoot it?””No, I didn’t even touch it,” replied Tyson. Cato was surprised because she had heard a different story when it happened a couple of years ago. It turned out some of the details were murky. Nothing bad happened but it was scary for the family.”Tyson, are you aware of these rules now?” Cato asked. Tyson replied in affirmative. This is the kind of conversation the museum is trying to foster. Even if visitors walk in with nearly no idea about firearms, the museum’s administrators hope that at least they can learn how to handle hard situations that firearms may present. Next, Hlebinsky took the Catos to the Cost of War exhibit. “As we’re walking into this gallery, really the first thing you encounter is this big graphic,” Hlebinsky said. “And some of the images you see when you walk into the gallery are the gravestones at the Arlington Cemetery and children affected by war.” The Catos also learned about Audie Murphy, the World War II veteran and actor who broke a taboo of the time by talking about his experience with what we would now call Post Traumatic Stress Disorder or PTSD. And the family learned that during the Civil War, some arms were produced by enslaved people. Multiple viewpoints The renovation tries to address the diverse audiences expected to visit. Hlebinsky said the museum offers different lenses through which people can learn about firearms, such as shooting sports, the technological evolution of firearms, and military history. Museum leaders say they also don’t want to ignore the current conversations around the misuse of firearms, specifically in mass shootings. The Catos ended their tour in front of a big black and white mural, produced by the artist known as JR in partnership with Time Magazine. Fifteen-year-old Jillian Cato described the mural this way: “It’s a big group of people. Many of them have signs. It seems to be a huge debate. One side is anti-gun and the other side is pro-guns rights.” The mural is derived from a video featuring images of Americans on all sides of the debate. Hlebinsky said as a museum curator, she can’t tell people what they should think about firearms. But she hopes the information spurs conversations among visitors. As the Cato family looked at the mural, the father, Kevin said they aren’t really gun enthusiasts. “I’m not into killing things. There’s no reason to have a gun unless you’re going to try to kill something,” he said. “I have really enjoyed this, though, and I’m going to do more research on the history of guns and how they are going to affect warfare.”That’s the goal of the new Cody Firearms Museum. Not to win people over as gun enthusiasts, but to help them learn and think about gun culture.Copyright 2019 Wyoming Public Radio. To see more, visit Wyoming Public Radio.center_img Kamila Kudelskalast_img read more

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The Best Laptops for Programming 2018

first_img Dell XPS 13 deals?US$1,500US$981.31ViewUS$1,499.99US$1,129.99ViewUS$1,279.99ViewUS$1,349.99ViewShow More DealsWe check over 130 million products every day for the best pricespowered by Asus ZenBook 13 UX331UN From $799.00 For programmers who prefer touch screens and AMD GPUs, this is the niche-specific laptop to get. Though it includes only 256GB of storage, it packs 16GB of RAM, a Core i7 CPU and a good assortment of ports, making it versatile enough for most programming situations. Its only major drawbacks are the loads of bloatware it comes with and its measly 7 hours of battery life.Key specs: CPU: 2.7-GHz Intel Core i7-7500U | RAM: 16GB | Storage: 256GB SSD | GPU: AMD Radeon 540 Graphics with 2GB of VRAM / Intel HD Graphics 620 | Display: 15 inches (1920 x 1080) | Weight: 3.8 poundsSamsung Notebook 9 Pro Review Amazon From $1299.99 Lenovo ThinkPad X1 Carbon deals?12 Amazon customer reviews☆☆☆☆☆US$750ViewUS$1,299.99ViewUS$2,349.99US$1,317.31ViewUS$1,329.11ViewShow More DealsWe check over 130 million products every day for the best pricespowered by For programmers with an affinity for AMD GPUs, this is a noteworthy entry on the list. The 15-inch Apple MacBook Pro sports a Radeon Pro 560, a 2.9-GHz Intel Core i7 processor and 16GB of RAM, meaning it’s equipped to be a programming workhorse. That 16GB of RAM is especially useful for juggling multiple intensive programs at once without hitting any lag or freezing. Plus, the 15-inch MacBook Pro sports impressive speakers. This MacBook Pro also rocks an 11 hour battery life. Worth noting, however, is that areas like the keyboard can run a little hot on the hands if you push this machine to its limits for a extended period.Key specs: CPU: 2.9-GHz quad-core Intel Core i7 | RAM: 16GB | Storage: 512GB | GPU: AMD Radeon Pro 560 | Display: 15.4 inches (2800 x 1800) | Weight: 4 poundsApple MacBook Pro 15-inch Review Apple MacBook Pro 15-inch (2018) deals?US$1,999.99ViewUS$2,079.99ViewUS$2,399US$2,198ViewUS$2,499ViewShow More DealsWe check over 130 million products every day for the best pricespowered by Asus ZenBook 13 UX331UN deals?US$1,999.11ViewNo price informationCheck WalmartWe check over 130 million products every day for the best pricespowered by Samsung Notebook 9 Pro Packing 8GB of RAM, a Core i5-8250U CPU and a GeForce MX150, the Asus ZenBook 13 UX331UN is a good lower-midtier option for coders looking to dig into computationally intensive programs. As proof of its graphics mettle, consider that this laptop ran Dirt 3 at 114 frames per second. As a bonus, the laptop sports a solid battery-life average of 9 hours and 11 minutes, meaning if you ever get really into a task without having a charger handy, you’ll have a good window of time to wrap things up. Also worth mentioning is that the ZenBook 13 sports a lot of useful ports, including two USB 3.0 ports, a microSD card reader and an HDMI port for connecting to an external monitor.Key specs: CPU: 1.6-GHz Intel Core i5-8250U | RAM: 8GB | Storage: 256GB | GPU: Nvidia GeForce MX150, Intel UHD Graphics 620 | Display: 13.3 inches (1920 x 1080) | Weight: 2.7 poundsAsus ZenBook 13 UX331UN Review Of all the laptops to make it onto this list, few are as capable as the Lenovo ThinkPad X1 Carbon. As our review states, this laptop has just about everything: a stunning HDR display, 11 hours of battery life, a best-in-class keyboard, and a lightweight, stylish design. Not to mention, the Carbon also packs 16GB of RAM and 512GB of storage. For those who want to look good while they work hard, this is the portable, powerful, premium programming laptop to get. Do note, though, that the sound from its speakers are rather tinny — so if you like what you see with the Carbon, you might want to grab a set of headphones in advance.Key specs: CPU: 1.6-GHz Intel Core i5-8250U | RAM: 16GB | Storage: 512GB SSD | GPU: Intel UHD Graphics 620 | Display: 14 inches (1920 x 1080) | Weight: 2.5 poundsLenovo ThinkPad X1 Carbon Review Microsoft Surface Pro This laptop is designed exclusively for the coders who believe that one man (or woman) should have all that power. If you plan on running the most graphically intensive programming software there is, you’re going to want the MSI GS65 Stealth Thin. It packs a beefy Nvidia GeForce GTX 1070 Max-Q GPU (which can run any game you throw at it), an intense 3.9-GHz Intel Core i7-8750H processor and 16GB of RAM. No matter what you need to run, or what you want to do, with this laptop, its specs mean it’ll (likely) be more than up to the task. Equipped with killer speakers, a 144-Hz display and a ton of ports (including HDMI), the GS65 Stealth Thin is a beast. Note, though, that all this performance comes at a cost, both financially and in terms of the heat this laptop produces.Key specs: CPU: 3.9-GHz Intel Core i7-8750H | RAM: 16GB | Storage: 512GB SSD | GPU: Nvidia GeForce GTX 1070 Max-Q | Display: 15.6 inches (1920 x 1080) | Weight: 4.1 poundsMSI GS65 Stealth Thin Review Dell Similar to the MSI GS65 Stealth Thin, the Razer Blade is a graphical powerhouse that packs a lot of impressive hardware into a petite, portable frame. If it can run Rise of the Tomb Raider at very high settings at 1080p averaging 77 fps, it’s more than equipped to tackle any graphically intensive task. Plus, it has a battery life of almost 6 hours, which is quite the rarity when dealing with laptops of this power tier. And it has an ever-useful HDMI port. Frankly, the Razer Blade’s only major programming-specific drawback would be its uncomfortable keyboard, which might hamper coders with killer word-per-minute rates.Key specs: CPU: 2.2-GHz Intel Core i7-8750H | RAM: 16GB | Storage: 512GB SSD | GPU: Nvidia GeForce GTX 1070 Max-Q | Display: 15.6 inches (1920 x 1080) | Weight: 4.6 poundsRazer Blade Review Razer Blade From $1799.00 Microsoft Surface Pro (2017) deals?610 Amazon customer reviews☆☆☆☆☆US$799US$598ViewUS$599ViewUS$799US$629ViewUS$1,449ViewShow More DealsWe check over 130 million products every day for the best pricespowered by From $1199.00 Amazon MSI GS65 Stealth Thin deals?US$1,180.59ViewUS$1,399.66ViewUS$1,599ViewUS$1,999US$1,886.78ViewShow More DealsWe check over 130 million products every day for the best pricespowered by Lenovo center_img Credit: Laptop Mag MSI GS65 Stealth Thin From $1519.00 HP Elitebook 840 G5 deals?US$1,569US$1,099.99ViewUS$1,254.89ViewUS$1,339.99ViewUS$1,345ViewShow More DealsWe check over 130 million products every day for the best pricespowered by From $2249.00 Bestbuy From $1899.99 Programming requires a very particular breed of laptop — the kind that’s equipped with processing power and hardware that might not be seen in everyday, average work machines. A smart set of baseline requirements for anyone shopping for a programming laptop include (at least) a Core i5 CPU, 8GB of RAM, a decent integrated graphics card and an SSD.These specs are a good set of buying guidelines, but they don’t narrow down the laptop selection pool nearly enough. To help you parse through the crowded marketplace, we compiled our top choices for programmers.MacBook Air vs MacBook Pro: Which 13-inch MacBook Is Right For You?Apple’s entry-level MacBook Air and Pro look pretty similar, but our testing proved they differ in crucial ways.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Which Cheap Tablet Is Best? Amazon Fire 7 vs Walmart Onn02:45关闭选项Automated Captions – en-USAutomated Captions – en-USAutomated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.laptopmag.com/articles/best-laptops-for-programming?jwsource=cl已复制直播00:0003:4603:46  Bestbuy Razer Blade (2018) deals?66 Amazon customer reviews☆☆☆☆☆US$1,599.99ViewUS$2,499.11ViewUS$2,999.11ViewUS$3,999.11ViewWe check over 130 million products every day for the best pricespowered by Amazon Samsung Notebook 9 Pro deals?36 Amazon customer reviews☆☆☆☆☆US$27.95ViewUS$1,049.99ViewUS$1,165ViewUS$1,249.99ViewShow More DealsWe check over 130 million products every day for the best pricespowered by Any programmer who needs a crisp, vibrant and (virtually) bezel-less screen for coding projects should take a good look at Dell’s XPS 13, which sports a notably attractive display. This machine is one of the slimmest on the entire list, making it great for working on the go, especially when you factor in its strong battery life. When you add in the machine’s 8GB of RAM and Core i7 CPU, it’s clear the XPS 13 isn’t just a looker; it packs a respectable hardware punch as well. However, it has zero USB Type-A ports, so be mindful of that.KeySpecs: CPU: 1.8-GHz Intel Core i7-8550U | RAM: 8GB | Storage: 256GB | GPU: Intel UHD Graphics 620 | Display: 13.3 inches (1920 x 1080) | Weight: 2.7 poundsDell XPS 13 Review Dell XPS 13 From $999.00 Lenovo ThinkPad X1 Carbon From $999.00 The HP EliteBook 840 G5 is a solid all-rounder, sporting a respectable 8-and-a-half-hour battery life, a Core i7 CPU, 16GB of RAM, 512GB of storage, quality audio and a well-designed keyboard. As with other laptops on the list, the 16GB of RAM is an especially valuable trait, as it enables the EliteBook to juggle a lot of heavy-hitting processes at once without crippling performance in the process. And, as icing on the cake, the machine also has an HDMI port, in addition to all the usual ones (a USB Type-C port, 3.0 port, headphone/mic jack, etc.).Key specs: CPU: 1.9-GHz Intel Core i7-8650U | RAM: 16GB | Storage: 512GB SSD | GPU: Intel UHD Graphics 620 | Display: 14 inches (1920×1080) | Weight: 3.4 poundsHP EliteBook 840 G5 Review Apple MacBook Pro 15-inch For programmers in need of a touch-screen-equipped laptop with requisite coding horsepower, Microsoft’s Surface Pro answers the call. Rocking a Core i7 CPU, 16GB of RAM and a hefty 1TB of storage, this laptop is great for programmers who like to stockpile tons of files. And it weighs only 1.7 pounds, meaning it’s perfect for travel. The Surface Pro’s only real drawback is its somewhat underwhelming 7-and-half-hour battery life.Key specs: CPU: 2.5-GHz Intel Core i7-7660U | RAM: 16GB | Storage: 1TB SSD | GPU: Intel Iris Plus Graphics 640 | Display: 12.3 inches (2736 x 1824) | Weight: 1.7 poundsMicrosoft Surface Pro Review HP EliteBook 840 G5 by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeKelley Blue Book5 Mid-engine Corvettes That Weren’tKelley Blue BookUndoGrepolis – Free Online GameGamers Around the World Have Been Waiting for this GameGrepolis – Free Online GameUndoTODAYPolice Identify Girl Licking Ice Cream Tub In Viral VideoTODAYUndoMy Food and FamilyHealthy, Homemade Drunken Thai Noodles In Just 20 MinutesMy Food and FamilyUndoVerizon WirelessThis new phone will blow your mind.Verizon WirelessUndo247 SportsThe Highest-Paid NBA Players In 2019, Ranked247 SportsUndoAdvertisementlast_img read more

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A Rare Beautiful Galaxy Is Inching Closer To The Milky Way

first_img The Milky Way galaxy tapestry print furniture decoration beach towel wall decoration (59W×7… (23) ENDS IN ENDS IN Bestseller $32.95$40.99 Ambesonne Modern Decor Tapestry by, Spiral Galaxy… Bestseller DEAL OF THE DAY All ENDS IN Close Millions and millions of galaxies exist beyond Earth, but due to the expansion of the universe, only a handful are headed toward the Milky Way.The breathtaking Messier 90, also known as M90 or NGC 4569, is one of these rare galaxies that seem to be on a path that will eventually take it to Earth.Meet The Messier 90NASA and ESA’s Hubble Space Telescope captured the image of the Messier 90 by combining visible, infrared, and ultraviolet light through the Wide Field and Planetary Camera 2. ENDS IN Bestseller ENDS IN Culturenik Spiral Galaxy Planet Space Nebula Stars Constellati… $19.99$19.99 DEAL OF THE DAY Wow facts 3Share this videoCopyPausePlay00:00% Buffered0PreviousPausePlayNextLive00:00 / 00:00UnmuteMuteExit fullscreenFullscreenCopy video urlPlay / PauseMute / UnmuteReport a problemLanguageBackMox PlayerDefaultEnglishEspañolУкраїнськаРусскийadvertisementIt’s a beautiful spiral galaxy that was discovered by the famous French astronomer Charles Messier on March 18, 1781.Located around 60 million light-years away from the Milky Way, it is a part of the constellation of Virgo. In fact, among more than 1,200 galaxies in the Virgo Cluster, Messier 90 is known to be the brightest member, according to Sci-News.The staircase-like shape seen in the picture is typical of the images produced by the camera, since the camera consisted of four light detectors with overlapping fields of view and one detector providing higher magnification than the rest, according to a statement from Hubble. When scientists stitched together the four images, they had to reduce the size of the image from this particular detector for the final image to be properly aligned.Messier 90’s Trajectory Toward The Milky WayOf course, it’s not the beauty of Messier 90 that makes it particularly rare, but its trajectory.Due to the constant expansion of the universe, nearly all of the galaxies that scientists detect are moving away from the Milky Way.Messier 90 is unique as it is actually traveling in the direction of Earth’s galactic neighborhood. Scientists know this because of the light coming from the spiral galaxy.In a phenomenon known as blueshift, the galaxy compresses the wavelength of its light as it comes closer to Earth in the same way a slinky is squashed when its pushed on one end. As a result, the frequency of light increases and appears on the blue end of the spectrum.”Astronomers think that this blueshift is likely caused by the cluster’s colossal mass accelerating its members to high velocities on bizarre and peculiar orbits, sending them whirling around on odd paths that take them both towards and away from us over time,” the Hubble statement revealed.The entire Virgo Cluster is actually traveling away from the Milky Way, but a number of galaxies within are moving faster than the cluster so that from Earth, it appears as if these galaxies are moving toward the Milky Way. TAG Spiral Galaxy, milky way, Galaxies Bestseller Ambesonne Modern Decor Curtains by, Spiral Galaxy A… (58) $28.99$37.73 DEAL OF THE DAY DEAL OF THE DAY AllVideo On Demand: Rent or BuyClothing & AccessoriesMajor AppliancesArts, Crafts & SewingAutomotiveBaby & NurseryBeauty & GroomingBooks & TextbooksCollectible CoinsCamera & PhotoCell Phones & AccessoriesClassical MusicComputers, Tablets & ComponentsBlu-Ray & DVDElectronic Components & Home AudioEntertainment CollectiblesVideo GamesOther Gift Card BrandsGrocery & Gourmet FoodPatio, Lawn & GardenHealth & HouseholdBusiness & Industrial SuppliesJewelryKindle StoreKitchen & DiningMagazinesMiscellaneousDigital MusicCDs & VinylMusical InstrumentsOffice & School SuppliesPet Food & SuppliesPatio, Lawn & GardenShoes, Handbags, Wallets, SunglassesSoftwareSports CollectiblesSports & FitnessHome ImprovementToys & GamesVHSVideo GamesWatches DEAL OF THE DAYcenter_img ENDS IN Space Map Milky Way Galaxy Spiral Stars Solar System Art Print Framed Poster Wall D… Bestseller Related Products DEAL OF THE DAY (45) Bestseller $29.95$35.99 Bestseller Ambesonne Modern Shower Curtain, Spiral Galaxy Andr… $9.95$9.95 ENDS IN ENDS IN $9.98$19.96 Ads by Amazon WEINIYA Bedroom Custom Decor Purple Charming Spiral Galaxy Milky Way Outer S… (1) $64.95$80.99 (101) DEAL OF THE DAY Spiral Galaxy Andromeda Milky Way Scarf for Women Soft Cozy Lightweight Scarf Shawl Wraps Bestseller DEAL OF THE DAY Ads by Amazon ⓒ 2018 TECHTIMES.com All rights reserved. Do not reproduce without permission.last_img read more

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Are these your keys

WebsiteWebsiteWebsite WebsiteWebsiteWebsite WebsiteWebsiteWebsite Click to receive news links via WhatsApp. Or  for the latest news, visit our webpage or follow us on Facebook and Twitter. Join us there! A set of keys was found in the Acaciavale area last week.A good Samaritan found the keys lying on the ground and came to the Ladysmith Gazette offices to drop it offIf the keys belong to you,  come to the Ladysmith Gazette office to claim them..

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first_img Figure 1. A high-fidelity 3-D tractography of the left ventricle heart muscle fibers of a mouse from Amsterdam Ph.D. researcher Gustav Strijkers. X-ray images such as the one on the left fail to indicate many cases of advanced bone destruction caused by multiple myeloma, says the author of new guidelines on imaging for patients with myeloma and related disorders. Image courtesy of Roswell Park Comprehensive Cancer Center. News | September 16, 2009 Lantheus to Study Safety of Novel PET Agent for Heart Failure News | PET-MRI | May 23, 2019 Study Explores Magnetic Nanoparticles as Bimodal Imaging Agent for PET/MRI Researchers from Bourgogne University in Dijon, France, showed that use of superparamagnetic iron oxide nanoparticles (… read more News | Radiopharmaceuticals and Tracers | July 01, 2019 Bracco Imaging Acquires Blue Earth Diagnostics Bracco Imaging S.p.A. has signed a definitive agreement to acquire Blue Earth Diagnostics, a molecular imaging company… read more Image courtesy of MR Solutions. News | PET-CT | June 19, 2019 United Imaging Announces First U.S. Clinical Install of uMI 550 Digital PET/CT United Imaging announced the first U.S. clinical installation of the uMI 550 Digital positron emission tomography/… read more News | PET-CT | August 15, 2019 United Imaging Announces First U.S. Clinical Installation of uExplorer Total-body PET/CT United Imaging announced that its uExplorer total-body positron emission tomography/computed tomography (PET/CT) system… read more News | Magnetic Resonance Imaging (MRI) | June 07, 2019 Amsterdam University Medical Center Wins MR Solutions’ Image of the Year Award The Amsterdam University Medical Center has won MR Solutions’ Image of the Year 2019 award for the best molecular… read more center_img Related Content News | Radiation Therapy | May 31, 2019 RefleXion Opens New Manufacturing Facility for Biology-guided Radiotherapy Platform RefleXion Medical recently announced the opening of its new manufacturing facility at its headquarters in Hayward,… read more News | Radiopharmaceuticals and Tracers | May 13, 2019 Blue Earth Diagnostics Expands Access to Axumin in Europe Blue Earth Diagnostics announced expanded access to the Axumin (fluciclovine (18F)) imaging agent in Europe. The first… read more News | Radiopharmaceuticals and Tracers | May 17, 2019 New Phase 2B Trial Exploring Target-Specific Myocardial Ischemia Imaging Agent Biopharmaceutical company CellPoint plans to begin patient recruitment for its Phase 2b cardiovascular imaging study in… read more September 17, 2009 – Lantheus Medical Imaging Inc. today announced the initiation of a Phase 1 clinical study to assess the safety, dosimetry and tolerability of LMI1195, a novel F-18 small molecule tracer for imaging cardiac neuronal function, in healthy subjects, undergoing positron emission tomography (PET) imaging. Heart failure is a serious medical condition, in which the heart muscle progressively loses its ability to pump blood, that affects more than five million people in the United States and results in about 1.1 million hospitalizations and 300,000 deaths each year.1,2 Patients with heart failure are six to nine times more likely than the general population3 to suffer sudden cardiac death as a result of abnormal cardiac neuronal function resulting in a fatal arrhythmia. According to the American Heart Association, the total cost of heart failure is estimated to be $37.2 billion in 2009, putting very significant health and financial burdens on patients, their families and society as a whole. “Given the high incidence of heart failure and associated deaths, there is a significant need to develop new diagnostic tools to help clinicians improve risk stratification and better identify heart failure patients at risk of arrhythmia and sudden cardiac death who might benefit from direct interventional therapy,” said D. Scott Edwards, vice president, global research and development, Lantheus Medical Imaging, Inc. “We look forward to the Phase 1 trial results and advancing the LMI1195 clinical development program.” The Phase 1 open-label, non-randomized, single-dose study will be conducted in the United States. The study is designed to estimate the radiation dosimetry of LMI1195 in healthy subjects undergoing a PET scan. The study will also evaluate the safety and tolerability of the tracer, gather pharmacokinetic and metabolic data, and assess PET imaging parameters and image quality. “The initiation of this study represents an important milestone in our strategy to develop a rich pipeline of diagnostic products to advance patient care,” said Don Kiepert, president and chief executive officer of Lantheus Medical Imaging, Inc. “LMI1195 is our second pipeline product to enter clinical development that uses molecular imaging and PET technology to improve cardiovascular imaging. We’re excited about the promise of this imaging agent to change how heart failure patients are evaluated.” References:1. National Heart Lung and Blood Institute, Heart Failure Fact Sheet 2007.2. American Heart Association,www.americanheart.mediaroom.com3. American Heart Association. Heart Disease and Stoke Statistics, 2009 Update. For more information: www.lantheus.com FacebookTwitterLinkedInPrint分享 News | Radiopharmaceuticals and Tracers | June 05, 2019 BGN Technologies Introduces Novel Medical Imaging Radioisotope Production Method BGN Technologies, the technology transfer company of Ben-Gurion University (BGU), introduced a novel method for… read more News | Computed Tomography (CT) | June 17, 2019 International Working Group Releases New Multiple Myeloma Imaging Guidelines An International Myeloma Working Group (IMWG) has developed the first set of new recommendations in 10 years for… read more last_img read more

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In shift Turkish jets strike Islamic State targets in Syria

first_imgA government statement said the airstrikes were approved Thursday after IS militants fired from Syrian territory at the Turkish military outpost, killing one soldier. A funeral was held Friday for the slain Turkish soldier, Yalcin Nane, where mourners denounced IS violence, the state-run Anadolu news agency reported.Officials said Friday’s airstrikes were codenamed “Operation Yalcin” in his honor.The agency said as many as 5,000 police officers were involved in Friday’s sweep against suspected extremists, which also targeted the PKK Kurdish rebel group and the outlawed far-left group DHKP-C. Davutoglu said those detained included 37 foreign nationals but did not name their home countries.One DHKP-C suspect, a woman, was killed in a gunfight with police in Istanbul, Anadolu reported.The agency said those detained in Istanbul included Halis Bayuncuk, an alleged IS cell leader in the city who is suspected of having helped recruit supporters.On Monday, a suicide bombing blamed on IS militants killed 32 people in Suruc, a Turkish town near the Syrian border. The bombing ignited protests from Turkey’s Kurds, who said the government had not done enough to prevent attacks from the IS group. Turkish police also launched a major operation Friday against extremist groups including the Islamic State, detaining more than 290 people in simultaneous raids in Istanbul and 12 provinces.Prime Minister Ahmet Davutoglu said the airstrikes Friday had “removed potential threats” to Turkey, hitting their targets with “100 percent accuracy.” He did not rule out further airstrikes, saying Turkey was determined to stave off all terror threats.“This was not a point operation, this is a process,” Davutoglu said. “It is not limited to one day or to one region … the slightest movement threatening Turkey will be retaliated against in the strongest way possible.”A government official said three F-16 jets took off from Diyarbakir air base in southeast Turkey early Friday and used smart bombs to hit three IS targets. The official spoke on condition of anonymity because of government rules requiring authorization for comment.Rami Abdurrahman, who heads the Britain-based Syrian Observatory for Human Rights said the three Turkish airstrikes were all near the border, hitting north of the village of Hawar al-Nahr, east of the Rai area and west of the town of Jarablous. Top Stories He said the airstrikes killed nine IS fighters, wounded 12 others and destroyed at least one IS vehicle and a heavy machine gun.The private Dogan news agency said as many as 35 IS militants were killed in the airstrikes, but did not cite a source.The Observatory also reported that an airstrike targeted a post near the border with Turkey for al-Qaida’s affiliate in Syria, the Nusra Front. It said it was not clear if Turkish warplanes or those of the U.S.-led coalition struck the Nusra Front position.Davutoglu said Turkish planes did not violate Syrian airspace Friday, but he did not rule out incursions in the future. He denied news reports claiming that Turkey had told the Syrian regime about the airstrikes, but said it had contacted NATO allies before the operation.The agreement on the Turkish air bases follows months of U.S. appeals to Turkey and delicate negotiations. Davutoglu said Friday that an agreement that takes Turkey’s concerns into account had been reached, but did not elaborate.Turkey’s moves came as the country finds itself drawn further into the conflict in neighboring Syria by a series of deadly attacks and signs of increased IS activity inside Turkey itself. Here’s how to repair and patch damaged drywall Ex-FBI agent details raid on Phoenix body donation facility Turkish officials say the Suruc bombing could be retaliation for Turkey’s crackdown on IS operations. In the last six months, more than 500 people suspected of working with the IS group in Turkey have been detained, officials say.___Butler reported from Istanbul. Bassem Mroue in Beirut and Josh Lederman in Washington contributed.Copyright © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. Mesa family survives lightning strike to home ANKARA, Turkey (AP) — In a major tactical shift, Turkish warplanes struck Islamic State group targets across the border in Syria on Friday, a day after IS militants fired at a Turkish military outpost. A Syrian rights group said the airstrikes killed nine IS fighters.Turkey, which straddles Europe and Asia and borders the Middle East, had long been reluctant to join the U.S.-led coalition against the extremist group.center_img Sponsored Stories Four benefits of having a wireless security system In a related, long-awaited development, Turkey said it has agreed to allow U.S.-led coalition forces to base manned and unmanned aircraft at its air bases for operations targeting the IS group.A Turkish Foreign Ministry statement said Turkey’s military would also take part in the operations.The ministry would not provide details on the agreement, citing operational reasons, but said it expected Turkey’s cooperation to “make a difference” to the campaign. The statement did not say which bases would be used, but Turkish media reports said they would include Incirlik, Diyarbakir and Batman, all in southern Turkey near the border with Syria.President Recep Tayyip Erdogan confirmed earlier that Turkey had agreed to let the U.S. use Incirlik air base for operations “within a certain framework.” A U.S. official said the agreement was reached during a phone call this week with President Barack Obama.In June 2014, the Islamic State group launched a blitz, capturing large parts of Iraq and of Syria — which has been ravaged by a four-year-old civil war. The group subsequently declared an Islamic caliphate on the territory it controls. The U.S.-led coalition has been striking the group in both Syria and Iraq. New Valley school lets students pick career-path academies 5 things to look for when selecting an ophthalmologist Comments   Share   5 treatments for adult scoliosislast_img read more

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Boat with 85 refugees lands in Pomos  Update

first_imgA boat with 85 Syrian migrants landed in Paphos early Friday afternoon, after departing from Turkey earlier this week, police said in a statement.The boat landed at the Paradise beach in Pomos at around 1.45pm, with 64 men, nine women and 12 children.Authorities went on site to transfer the migrants to the nearest police station for identification.Four requested medical assistance and were transferred to the Polys Chrysochous hospital and were later released. No serious injuries have been reported.The migrants said they had departed from a Turkish port on Wednesday paying their smuggler $2,000 (€1,750) each. Where families were concerned, a discounted price was offered, it emerged.Paphos police is currently investigating whether the smuggler is one of the 85 Syrians that arrived in the boat.Civil defence, the Red Cross and social welfare officers met with the migrants offering assistance and food.Authorities were trying to evaluate whether all 85 migrants could be transferred to the Kokkinotrimithia reception centre.  You May LikeFigLeaf Beta AppTake Online Privacy on a whole New levelFigLeaf Beta AppUndoYahoo Search | Search AdsStop Joint Pain. Search Joint Pain ReliefYahoo Search | Search AdsUndoDr. Marty3 Dangerous Foods People Feed Their Dogs (Without Realizing It)Dr. MartyUndo Pensioner dies after crash on Paphos-Polis roadUndoTurkish Cypriot actions in Varosha ‘a clear violation’ of UN resolutions, Nicosia saysUndoRemand for pair in alleged property fraud (Updated)Undoby Taboolaby Taboolalast_img read more

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Mathiatis groups slam mining companys trojan horse plan to extract gold

first_imgCitizen initiative groups in the Strongylos-Mathiatis region have expressed their opposition to Hellenic Copper Mines’ new request for the removal of mine waste from the area and its restoration, calling it “a trojan horse” for the extraction of remaining gold reserves, which they also oppose.Hellenic Copper Mines has recently submitted a proposal for the removal of mine waste and restoration of Strongylos mine in south Mathiatis, following the rejection of their previous proposal, which also contained plans for the extraction of remaining gold reserves.The rejection of the original plan was made on the basis of the antiquities department’s position regarding the possible existence of ancient artefacts within the mine.The group for the protection of the historic and environmental wealth of Mathiatis as well as the group of residents affected by the reopening of the south Mathiatis mine have called attention to the negative environmental, archaeological and cultural impacts of the mining company’s proposal.The Strongylos mine, which is on the tentative list of Unesco World Heritage Monuments as part of the Troodos Mountain ophiolite – a 90-million-year-old fragment of well-preserved oceanic crust and an excellent example of volcanogenic massive sulphide deposit – is about 2km south of Mathiatis community and is a gold mine dating back to 600BC.The groups said that the proposal to move the three stacks of waste and to restore the area with a play area, a park, parking, kiosks, benches and pathways, “involves disrupting the area, altering the geomorphology, cutting tens of pine trees, significant deterioration of the flora and disturbance of the fauna of the region.”The groups referred to the proposed plan as “the trojan horse for the degradation, alteration and destruction of the southern mine’s important and unique natural and cultural landscape, all with the aim of further exploiting the remaining gold reserves in the wider region.”The two groups suggest that it would be in the public interest to create “a model archaeological and environmental park with international recognition as a UNESCO World Heritage Site”.You May LikeAmiraspantry.comMediterranean Chickpea SaladAmiraspantry.comUndoOrganic Welcome9 Best Drinks For Knee and Joint PainOrganic WelcomeUndoAmazon | Moral PanicRead the novel that will make you rethink your internet securityAmazon | Moral PanicUndo Greek Prime Minister in Cyprus for official visitUndoLED-lighting the way by 2020UndoFilms and food at RialtoUndoby Taboolaby Taboolalast_img read more

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